Scientific Training for Post-Translational Modification Detection in Cancer Screening (STRIM)

Project summary

Early detection at more manageable stages of cancer can improve prognosis, treatment options, and survival rates. However, this necessitates the identification of proper biomarkers and their quick and accurate detection, desirably, in blood, at low concentrations through sensitive assays and sensors. With the support of the Marie Skłodowska-Curie Actions programme, the STRIM project will focus on the identification and detection of aberrant post-translational modifications of proteins and nucleic acids in cancer.

The consortium will train doctoral candidates in the development of bioinformatic approaches for biomarker discovery, electrochemiluminescence-based screening tools, and regulatory health technology assessments for social acceptability of the produced tests and devices for cancer detection. Collectively, STRIM deliverables are expected to improve the accuracy and speed of cancer diagnostics.