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Gender differences in susceptibility to cognitive conditions due to the X-chromosome

Project summary

Men and women have different chances to suffer from cognitive conditions. For example, autism has a higher frequency in men and anxiety conditions occur more in women. Because women have two X-chromosomes and men only one, women have to silence one X-chromosome. How this works is not well known and may explain some male-female differences. The researchers will investigate the silencing of the X-chromosome and hope to find an explanation for the mentioned gender differences.

More detailed information

Principal Investigator:

Dr. M.C. Gontan

Role Erasmus MC:



Developmental Biology

Project website:

Not available

Funding Agency: