(IFEROA) Identification of the female specific etiology and risk groups for osteoarthritis

Project summary

Arthrosis is the most frequent type of rheumatism and also the fastest growing cause to physical limitations. It occurs twice as often in women after menopause as in men. It also results in more physical limitations in women than in men, suggesting there are female specific biological processes leading to arthrosis.
The focus of this research is to map these processes using studies containing data on joints and on molecules that are linked to metabolic processes to discover female specific markers and processes.

This research aims to identify predictors that could identify women with a high risk for arthrosis. In addition it aims to find targets that can influence female specific processes that could lead to decrease and inhibition of arthrosis.