Impact of obesity on the start of life

Project summary

Obesity of the mother, before and during pregnancy, leads to increased risks of cardiovascular diseases in their offspring. It is not known how maternal obesity increases this risk of adverse offspring health outcomes. This research examines the impact of maternal obesity on the development of the placenta and the embryo in the earliest phase of life, the subsequent effects on offspring cardiovascular health throughout the life-course and potential next steps to prevent these detrimental effects in offspring.