Intrinsic neuronal control of neurotropic virus infection

Project summary

Virus infections of the human nervous system can have severe deleterious consequences, including neonatal infections with permanent sequelae, eye infections that can lead to permanent blindness, and potentially fatal inflammation of the brain. In this project, it will be investigated how neuronal cells arm themselves against incoming viruses to prevent infection and virus proliferation. Understanding these protective processes is a crucial step towards the development of improved therapeutics to combat virus infections and prevent serious damage to the fragile nervous system.