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(PIONEER) Prostate Cancer DIagnOsis and TreatmeNt Enhancement through the Power of Big Data in EuRope

Project summary

Prostate Cancer (PCa) is the second leading cause of cancer, among men in Europe. There are currently major unmet needs in this field, such as insufficient knowledge on risk factors that contribute to PCa and on patient characteristics (including genetic profiles) that could facilitate patient stratification. Finally, there is lack of meaningful engagement of all key stakeholders, while the knowledge currently gained from clinical practice and real life data is not being fed back into PCa patients’ care pathways. There is thus a need for better definition of PCa across all stages, improved patient’s stratification at diagnosis, and standardisation of PCa-related outcomes based on real life data. PIONEER’s unique dual approach is to first identify critical evidence gaps in PCa by respected Key Opinion Leaders, and then embark on a research priority setting exercise that reflects the needs of all key stakeholders in  PCa management.


PIONEER will harness the power of big data to transform the field of prostate cancer research from the perspective of all relevant stakeholders including clinicians, pharmaceutical companies, payers and most importantly patients. Together we can ensure each individual patient receives the right treatment for them at the right time.

More detailed information

Principal Investigator:

Prof. dr. Monique Roobol

Role Erasmus MC:



Project website:

Funding Agency:

Innovative Medicines Initiative (IMI)