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Resistance to breast cancer drugSCO-101

Project summary

The new-still premature drug, working title SCO-101, is intended to ensure that breast cancer tumor cells are no longer resistant to the drug used to treat them. This resistance occurs in a significant proportion of breast cancer patients treated with tamoxifen. This is a drug that is prescribed as a follow-up treatment to prevent any metastases from growing into new tumors.



For all currently known genes that cause the tumor cell to become resistant to tamoxifen, he will investigate whether SCO-101 is able to reverse the resistance. And if so, try to clarify through which mechanism SCO-101 accomplishes this.

More detailed information

Principal Investigator:

John Martens

Role Erasmus MC:




Project website:

Not available

Funding Agency:

Funding Agency