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Targeting chromatin environment around DNA replication fork to destabilize tumor cell proliferation

Project summary

Unregulated DNA replication can provide limitless proliferation potential to tumor cells. The mechanisms regulating DNA replication machinery are poorly understood. This research focuses on identifying the specific chromatin organization signatures during replication in cancer cells and target those to cause instability of DNA replication process in cancer cells

More detailed information

Principal Investigator:

Dr. N. Taneja

Role Erasmus MC:



Molecular Genetics

Project website:

Not available

Funding Agency: