Dementia is a complex disorder with multiple causes. Both predisposition factors (genetics) and environmental factors cause changes in the brain that ultimately lead to dementia. It is impossible to investigate all these factors in one cohort. By sharing, harmonizing and researching data from various existing cohorts, the new Netherlands Consortium of Dementia Cohorts (NCDC) consortium hopes to better understand how the disease originates. In this way, new targets can be found for the prevention of dementia.
The NCDC will conduct research into the prevention of dementia, based on data collected for a long time in nine Dutch cohorts. For research into the prevention of dementia, data from a total of 200,000 people are being studied in conjunction with each other. The research will relate predisposition factors and environmental factors to brain changes that occur with dementia, including Alzheimer’s disease and vascular dementia, and with memory function and daily functioning.