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Treatment of brain stem cancer in children

Project summary

The aim of the new research project is to see by means of PET-MRI whether intra-arterial administration combined with opening of the blood-brain barrier does indeed lead to a higher uptake of tumor chemotherapy compared to standard administration. The methods will first be examined in adult patients with brain tumors before being translated into studies for children with DIPG. This will take place at the Princess Máxima Center in Utrecht where children with DIPG are treated centrally.


It is expected that chemotherapy will reach the tumor better while it spreads less in the rest of the body, thereby aiming for more effect and fewer side effects in patients.

More detailed information

Principal Investigator:

Dr. Sophie Veldhuijzen van Zanten

Role Erasmus MC:



Project website:

Not available

Funding Agency: